Glasgow: Scientists are investigating a new therapy for the treatment of
tendon injuries such as tennis elbow and Achilles tendinitis after
gaining new insight into the condition. Tendon injuries (tendinopathies) are common, accounting for 30-50% of
all sporting injuries, and are usually caused by repetitive strain or
major trauma.
While many people recover after a period of rest, a significant
number of people do not because the structure of the tendon itself has
permanently weakened. Healthy tendons, connecting muscles to bones, are primarily composed
of type-1 collagen, a very strong material. When injured the body
responds by producing the inferior type-3 collagen to quickly repair the
damage. This type of collagen is not as strong as type-1 and is more
prone to damage. Normally, over time, type 3 is replaced by the stronger
type-1.
However, in some people, repetitive damage means the body never
replaces the weaker type-3 collagen, leaving them with inherently weaker
tendons and long-term symptoms, such as pain and reduced mobility.
Scientists at the University of Glasgow are trialling a new therapy
(TenoMiR™) for treating tendinopathy after being awarded a High Growth
Spinout grant from Scottish Enterprise.