Xeroderma pigmentosum

Xeroderma pigmentosum (literally dry pigmented skin), is defined by extreme sensitivity to sunlight, resulting in sunburn, pigment changes in the skin and a greatly elevated incidence of skin cancers. About 60% of affected individuals show an exaggerated and prolonged sunburn response. In a minority of cases there are neurological abnormalities of varying severity. Historically, the disorder was classified originally as "classical XP" (skin abnormalities only) and the De-Sanctis-Cacchione syndrome with skin abnormalities and extreme neurological degeneration. The latter term is currently rarely used as it is evident that there is a wide range of neurological abnormalities of varying severity and varying age of onset. Thus, the complete De Sanctis-Cacchione syndrome is present in only very few cases, but several patients have one or more neurological features.

Xeroderma pigmentosum

Xeroderma pigmentosum (XP) is defined by extreme sensitivity to sunlight, resulting in sunburn, pigment changes in the skin and a greatly elevated incidence of skin cancers.
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Xeroderma pigmentosum (in short)

Xeroderma pigmentosum (XP) is defined by extreme sensitivity to sunlight, resulting in sunburn, pigment changes in the skin and a greatly elevated incidence of skin cancers.