Citrus Fruit Consumption Associated with Increased Melanoma Risk

Journal of Clinical Oncology: Citrus products are widely consumed foods that are rich in psoralens and furocoumarins, a group of naturally occurring chemicals with potential photocarcinogenic properties. The risk of cutaneous malignant melanoma associated with citrus consumption was evaluated.
The risk was : +10%  for two to four times per week, +26% for five to six times per week, +27% for once to 1.5 times per day, and +36% for ≥ 1.6 times per day.  Among individual citrus products, grapefruit showed the most apparent association with risk of melanoma, which was independent of other lifestyle and dietary factors.
Conclusion: Citrus consumption was associated with an increased risk of malignant melanoma in two cohorts of women and men. Nevertheless, further investigation is needed to confirm our findings and explore related health implications.