Menopausal antidepressants may boost bone fracture risk

Scimex: The class of antidepressants known as SSRIs (selective serotonin reuptake inhibitors), taken to curb menopausal symptoms, may boost bone fracture risk, a US study has found. The researchers say that women who had been prescribed SSRIs were at a 76 per cent increased risk of a fracture one year after starting treatment, 73 per cent after 2 years, and 67 per cent after 5 years, compared to women who were on another type of drug used to treat indigestion.

Old Bones Can Regain Youthful Healing Power

Durham: Broken bones in older people are notoriously slow to heal, but researchers at Duke Medicine have identified a potential way to speed the process.In studies using mice, the researchers not only traced what signals go wrong when aged bones heal improperly, they also successfully manipulated the process by both circulating blood and transplanting bone marrow from a young mouse into an older mouse, prompting the bones to heal faster and better. The findings, reported online May 19, 2015, in the journal Nature Communications, address one of the largest problems draining health care resources. According to the Centers for Disease Control and Prevention, fractures are the most common and costly nonfatal injuries to adults over age 65. They account for more than one-third of that population’s nonfatal injuries, and 61 percent of total nonfatal care costs.

Both weight loss and weight gain linked with increased fracture risk

BMJ. UK: Both weight gain and weight loss in older (postmenopausal) women are associated with increased incidence of fracture, but at different anatomical sites, finds a study published in The BMJ this week.
The findings also challenge the traditional view that weight gain protects against fractures.