Harmful effects of a commonly used cancer drug can be alleviated by using gene therapy

Helsinki: Doxorubicin treatment, which is commonly used in a variety of cancers, leads to cardiac atrophy and body wasting. Researchers from the Wihuri Research Institute and the University of Helsinki found that in mouse heart, doxorubicin leads to blood vessel rarefaction, which was prevented by treatment with gene therapy using the VEGF-B growth factor.