“What we observed is that exercise improves diabetes control regardless of improvement in exercise capacity,” said Dr. Jarett Berry, Associate Professor of Internal Medicine and Clinical Sciences at UT Southwestern, and co-senior author of the study.
Following an exercise training program generally improves fitness. Researchers typically measure fitness by the ability of the respiratory system to exchange carbon dioxide and oxygen. The more you train, the better your ability to take in oxygen.
But a sub-group of exercisers, considered non-responders, are unable to improve their cardiorespiratory fitness levels despite diligent exercise, explained Dr. Ambarish Pandey, a cardiology fellow at UT Southwestern and first author on the study appearing in Diabetes Care. About 30 percent of exercisers are considered non-responders.
Using data from the Health Benefits of Aerobic and Resistance Training in Individuals With Type 2 Diabetes (HART-D) trial, researchers looked at whether non-responders who exercised saw improvements in their diabetes control.
“We were interested in the relationship between the change in cardiorespiratory fitness, or exercise capacity, and change in metabolic parameters,” said Dr. Berry, a preventive cardiologist and Dedman Family Scholar in Clinical Care.
Researchers divided people into four groups:
- Controls, who did not exercise;
- Individuals who did aerobic exercise;
- Individuals who did resistance training;
- Individuals who did a combination of aerobic exercise and resistance training.
“This finding suggests that our definition of ‘non-responder’ is too narrow. We need to broaden our understanding of what it means to respond to exercise training,” Dr. Berry said.
The study proposes that exercise-training programs for people with Type 2 diabetes should measure improvements in glycemic control, waist circumference, and percentage of body fat.