Colorado: While dietary supplements may be advertised to promote health, research shows that over-the-counter
supplements may actually increase cancer risk if taken in excess of the
recommended daily amount. “We are not sure why this is happening at the molecular level but
evidence shows that people who take more dietary supplements than needed
tend to have a higher risk of developing cancer,” explains Byers,
associate director for cancer prevention and control at the CU Cancer
Center.
The line of research started 20 years ago with the observation that
people who ate more fruits and vegetables tended to have less cancer.
Researchers including Byers wanted to see if taking extra vitamins and
minerals would reduce cancer risk even further.
“When we first tested dietary supplements in animal models we found
that the results were promising,” says Byers. “Eventually we were able
to move on to the human populations. We studied thousands of patients
for ten years who were taking dietary supplements and placebos.”
The results were not what they expected.
“We found that the supplements were actually not beneficial for their
health. In fact, some people actually got more cancer while on the
vitamins,” explains Byers.
One trial exploring the effects of beta carotene supplements showed
that taking more than the recommended dosage increased the risk for
developing both lung cancer and heart disease by 20 percent. Folic acid,
which was thought to help reduce the number of polyps in a colon,
actually increased the number in another trial.
“This is not to say that people need to be afraid of taking vitamins
and minerals,” says Byers. “If taken at the correct dosage,
multivitamins can be good for you. But there is no substitute for good,
nutritional food.”
Byers says that people can get the daily recommended doses of
vitamins and minerals in their diets by eating healthy meal and that
many adults who take vitamin supplements may not need them.
“At the end of the day we have discovered that taking extra vitamins and minerals do more harm than good,” says Byers.