Friday, March 13, 2015

Predicting unpredictable diseases

Scimex: Mathematical models predicting and preventing disease spread will only be effective if scientists around the world collaborate closely, an international group of disease specialists has warned.

The group of 22 scientists and mathematicians were co-authors of a paper published today in the prestigious journal Science, demonstrating how mathematical modelling is a valuable toolkit that can account for factors such as emergence of new pathogens, genetic evolution of diseases and international travel.
One of them, Professor Mick Roberts from Massey University's Institute of Natural and Mathematical Sciences says the threat from infectious diseases is ongoing. "Memorable successes like the eradication of smallpox are isolated events. New emerging diseases still present a challenge – a challenge that we can face with mathematical modelling if we do it right."
The paper uses the example of the recent outbreak of Ebola in West Africa and how scientists were able to predict the short-term growth of the epidemic to plan for bed capacity. When initial attempts to contain the epidemic were unsuccessful, modelling was used to determine the most effective interventions – such as setting up novel types of treatment centres.
It also highlights influenza and human immunodeficiency virus (HIV) as examples of the success of mathematical modelling for planning responses.
One of the barriers scientists face is under-reporting of cases or transmission. This is in part being solved by mathematical software becoming more accessible and often free online. Professor Roberts says the key is to continue to share more information as widely as possible.
"There is a mismatch between where scientists are and where diseases are emerging. We need to empower local scientists to collaborate with governments and other scientists around the world.
"Mathematical models will help us shape successful local and global public health policies."