CDC. US: Lassa fever is an acute viral illness that occurs in west Africa.
The illness was discovered in 1969 when two missionary nurses died in
Nigeria. The virus is named after the town in Nigeria where the first
cases occurred. The virus, a member of the virus family Arenaviridae, is a single-stranded RNA virus and is zoonotic, or animal-borne.
Lassa fever is endemic in parts of
west Africa including Sierra Leone, Liberia, Guinea and Nigeria;
however, other neighboring countries are also at risk, as the animal
vector for Lassa virus, the "multimammate rat" (Mastomys natalensis)
is distributed throughout the region.
In 2009, the first case from
Mali was reported in a traveler living in southern Mali; Ghana reported
its first cases in late 2011. Isolated cases have also been reported
in Côte d’Ivoire and Burkina Faso and there is serologic evidence of
Lassa virus infection in Togo and Benin.
The number of Lassa virus infections
per year in west Africa is estimated at 100,000 to 300,000, with
approximately 5,000 deaths. Unfortunately, such estimates are crude,
because surveillance for cases of the disease is not uniformly
performed. In some areas of Sierra Leone and Liberia, it is known that
10%-16% of people admitted to hospitals every year have Lassa fever,
which indicates the serious impact of the disease on the population of
this region.