INSERM. France: Bisphenol A is a chemical compound that is included in the
composition of plastics and resins. It is notably used in the
manufacture of food containers and is also found in the protective films
used inside food and beverage cans. Several studies have shown that
this component has harmful effects on reproduction, metabolism and the
brain. The full impact of bisphenol A occurs during foetal life.
Testosterone produced by the testes in humans and mammals during
foetal life is necessary for the masculinisation of internal and
external genitalia. Without this hormone, these organs can spontaneously
develop in a female sense. A decrease in foetal testosterone production
can lead to defects in masculinisation observed at birth (such as
hypospadias and cryptorchidism). Furthermore, it is likely that a lack
of testosterone produced during foetal life can result in a reduced
sperm count in adulthood.