Thursday, May 3, 2012

Ovarian Cancer (risk factors)

serous cystadenocarcinoma. Radiopaedia
Authors: Cancer Epidemiology Unit, University of Oxford, Oxford, United Kingdom PLos Medicine 2012-04-03

Cancer of the ovaries, usually referred to as ovarian cancer, is the fifth leading cause of cancer death in women, and, unfortunately, symptoms (such as abdominal pain and swelling) usually occur late in the disease process; fewer than one-third of ovarian cancers are detected before they have spread outside of the ovaries. There is no definitive evidence that screening reduces mortality from ovarian cancer, and given the poor prognosis of advanced ovarian cancer, there has been much research over recent years to increase understanding of this serious condition. There are recognized risk factors that increase the chance of developing ovarian cancer, such as increasing age, having fewer children, not having used oral contraceptives, and use of menopausal hormone therapy. Age and oral contraceptive use have by far the biggest impact on ovarian cancer risk. Ovarian cancer is also associated with height (increase) and, among never-users of hormone therapy, with body mass index (increase).