Scientists Discover Biological Evidence of "Atypical" Chronic Fatigue Syndrome

Columbia: Scientists at the Center for Infection and Immunity (CII) at Columbia University’s Mailman School of Public Health are the first to report immune signatures differentiating two subgroups of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS): “classical” and “atypical.” This complex, debilitating disease is characterized by symptoms ranging from extreme fatigue after exertion to difficulty concentrating, headaches, and muscle pain.The study appears in the Nature Publishing Group journal, Translational Psychiatry.

Exercise as treatment for patients with chronic fatigue syndrome

Cochrane: Chronic fatigue syndrome (CFS) is sometimes called myalgic encephalomyelitis (ME). Research estimates that between 2 in 1000 and 2 in 100 adults in the USA are affected by CFS. People with CFS often have long-lasting fatigue, joint pain, headaches, sleep problems, and poor concentration and short-term memory. These symptoms cause significant disability and distress for people affected by CFS. There is no clear medical cause for CFS, so people who are affected often deal with misunderstanding of their condition from family, friends and healthcare professionals. National Institute for Health and Care Excellence (NICE) guidelines recommend exercise therapy for individuals with CFS, and a previous review of the evidence suggested that exercise therapy was a promising approach to the treatment. It is thought that exercise therapy can help management of CFS symptoms by helping people gradually reintroduce physical activity into their daily lives.

Scientists find genetic changes associated with chronic fatigue syndrome

Scimex: Australian researchers say they’ve found genetic changes associated with chronic fatigue syndrome (CFS, also known as Myalgic Encephalomyelitis or ME). The results could help settle a long-standing debate about whether the condition, initially dismissively referred to as ‘yuppie flu’, is purely psychological or whether it has a biological cause in the body. The scientists identified genetic changes in receptors associated with immunological and cellular function, which they say disrupt signalling mechanisms involving the detection and response to threats.

Scientists Find Clues Into Cognitive Dysfunction in Chronic Fatigue Syndrome

Columbia: Scientists at Columbia University’s Mailman School of Public Health have identified a unique pattern of immune molecules in the cerebrospinal fluid of people with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) that provides insights into the basis for cognitive dysfunction—frequently described by patients as “brain fog”—as well as new hope for improvements in diagnosis and treatment.

Potential biomarkers for chronic fatigue syndrome

Scimex: Researchers have identified distinct immune changes in patients diagnosed with chronic fatigue syndrome, known medically as myalgic encephalomyelitis or systemic exertion intolerance disease. The findings could help improve diagnosis and identify treatment options for the disabling disorder, in which symptoms range from extreme fatigue and difficulty concentrating to headaches and muscle pain.

Immune changes found in people with CFS/ME

NHS. UK: "Distinct stages to chronic fatigue syndrome identified," reports BBC News online. People with chronic fatigue syndrome (CFS), sometimes called myalgic encephalopathy (ME), can have debilitating exhaustion affecting their everyday life that does not go away with sleep or rest.

Scientists Discover Robust Evidence That Chronic Fatigue Syndrome Is a Biological Illness

Columbia University. US: Researchers at the Center for Infection and Immunity at Columbia University’s Mailman School of Public Health identified distinct immune changes in patients diagnosed with chronic fatigue syndrome, known medically as myalgic encephalomyelitis (ME/CFS) or systemic exertion intolerance disease.

Is exercise as treatment for patients with chronic fatigue syndrome positive?

Cochrane: Chronic fatigue syndrome (CFS) is sometimes called myalgic encephalomyelitis (ME). Research estimates that between 2 in 1000 and 2 in 100 adults in the USA are affected by CFS. People with CFS often have long-lasting fatigue, joint pain, headaches, sleep problems, and poor concentration and short-term memory.

US panel redefines chronic fatigue syndrome

Nature: The mysterious disease known as chronic fatigue syndrome (CFS) has long defied classification, because the symptoms vary greatly in the millions of people who are affected by it. Now, a panel commissioned by the US Department of Health and Human Services (HHS) has produced what is sure to be an influential report on how the disease should be diagnosed. The guidelines come with a new moniker: systemic exertion intolerance disease (SEID).

US panel redefines chronic fatigue syndrome

Nature: The mysterious disease known as chronic fatigue syndrome (CFS) has long defied classification, as the millions of people who suffer from it show a wide variety of symptoms. Now a panel commissioned by the US Department of Health and Human Services (HHS) has produced what is sure to be an influential report on how the disease should be diagnosed. This new definition comes with a new moniker: systemic exertion intolerance disease (SEID).

How therapy and exercise may help some with chronic fatigue syndrome

NHS. UK: "Chronic fatigue syndrome patients' fear of exercise can hinder treatment," The Guardian reports. Chronic fatigue syndrome (CFS) is a long-term condition that causes persistent and debilitating fatigue. We do not know what causes the condition and there is no cure, though many people improve over time.
Treatments for CFS aim to reduce symptoms, but some people find certain treatments help, while others don't.

Chronic fatigue syndrome

Chronic fatigue syndrome is  characterized by intense fatigue of unknown cause, which is permanent and limits the patient's functional capacity, producing various degrees of disability.
It combines, since at least six months :

• a sensation of intense tiredness, of infectious kind, with at least 50 % reduction of daily activity;
• memory, concentration, and mood disorders, which can remind of a depressive or generalized anxiety chart
• functional disorders  (locomotor, digestive, cardio-respiratory...) like "somatization" symptoms (hypocondria, hysteria...).
• Sleep disorders: insomnia, hypersleepiness 

More about chronic fatigue syndrome

Chronic fatigue syndrome

Source: Alfredo Avellaneda Fernández, Álvaro Pérez Martín and coll. BMC Psychiatry.

What is chronic fatigue syndrome?

The chronic fatigue syndrome (CFS) is fundamentally characterized by intense fatigue of unknown cause, which is permanent and limits the patient's functional capacity, producing various degrees of disability.

Chronic Fatigue Syndrome

Author: Dr Peremarty MD. Chronic fatigue syndrome.

An invisible sleep pathology, "wake up more tired than the day before"

An illness on the border between psychology and physiology...

Definition:
CFS is a clinical chart which combines, since at least six months :

• a sensation of intense tiredness, of infectious kind, (with, sometimes, a feeling of a little fever or swollen ganglions), carrying with it a significant reduction (at least 50 %) of daily activity;
• memory, concentration, and mood disorders, which can remind of a depressive or generalized anxiety chart;