Scimex: Pessimism seems to be a strong risk factor for death from coronary 
heart disease (CHD), while optimism does not protect from it, according 
to a study published in the open access journal BMC Public Health that involved 2,267 middle aged and older Finnish men and women. Researchers
 at the Department of Psychiatry, Päijät-Häme Central Hospital, Finland,
 found that people with high levels of pessimism seemed to have a higher
 risk of CHD-induced mortality, even after adjusting for known 
physiological risk factors. Optimism did not seem to have any effect on 
that risk.
Optimism and pessimism in the scientific sense focus on
 people’s attitude towards their future – whether or not they generally 
expect a greater number of desirable or undesirable things to happen. 
Dr. Mikko Pänkäläinen, lead author of the study said: “High levels of 
pessimism have previously been linked to factors that affect cardiac 
health, such as inflammation, but data on the connection between risk of
 death from CHD and optimism and pessimism as personality traits are 
relatively scarce.”
Dr. Pänkäläinen added: “Levels of pessimism 
can be measured quite easily and pessimism might be a very useful tool 
together with other known risk factors such as diabetes, hypertension or
 smoking to determine the risk of CHD-induced mortality.”
This is 
the first study to examine CHD mortality and its association with 
optimism and pessimism as independent variables. Previous research that 
treated optimism and pessimism as opposites on a continuous scale 
rendered conflicting results, particularly regarding associations 
between optimism and CHD-related deaths.
The researchers found 
that the 121 men and women who died from CHD during the study’s 
eleven-year follow-up period had been more pessimistic at baseline than 
people who were still alive at follow-up. However, there was no 
difference between the groups in optimism, suggesting that pessimism 
alone mediates the effect on CHD mortality. Comparing the highest and 
lowest quartiles of pessimism, people in the highest quartile had a 
2.2-fold higher risk of dying from CHD than those in the lowest 
quartile.
To investigate possible associations between optimism, 
pessimism and CHD mortality, the researchers used baseline data, 
collected in 2002 as part of the GOAL (Good Ageing in Lahti region) 
study, on 2,267 Finnish men and women who, at the start of the study 
period, were between 52 and 76 years old. The GOAL data provided 
information on socioeconomic status, psychosocial background, and 
lifestyle, as well as health data including blood glucose levels, blood 
pressure, use of hypertension or diabetes drugs, and prior diagnoses of 
CHD.
At baseline, study subjects also filled out the revised 
version of the Life Orientation Test (LOT-R), a questionnaire that 
includes six statements, three of which indicate optimism – for example 
“in uncertain times, I usually expect the best” – and three of which 
indicate pessimism, for example “if something can go wrong for me, it 
will”. Respondents were asked to indicate how well these statements 
described them, as expressed on a scale from 0 (not at all) to 4 (very 
much so).
Observational studies like this one can show possible 
links between risk of death from CHD and pessimism, but they cannot show
 cause and effect because other factors may play a role. While this 
prospective cohort study investigated a randomly selected group of 
people with even numbers of both sexes and representatives of all 
invited age groups across a long follow-up period, it may be limited by 
its use of self-reported data which may have caused inconsistencies 
between people’s answers and the reality of some physiological risk 
factors such as smoking habits or use of medications.